Cell and Molecular
Biology (CMB) is a degree-granting unit within the
Molecular Biosciences cluster, which
Biochemistry and Molecular Biophysics (BMB)
• Committee on Developmental
on Genetics, Genomics & Systems Biology (GGSB)
• Human Genetics.
The academic units of the cluster share a core
curriculum and a common admissions process.
The goal of the doctoral program in Cell and
Molecular Biology is to foster advanced scholarship and research
in the combined areas of cell biology, genetics, and molecular biology.
Students are introduced to a broad spectrum of experimental rationales
and technical approaches and typically learn several in depth. Skills
in genetic analysis include transgenic, reverse genetic, and genomic
analysis, as well as molecular analysis of genes and gene products.
Skills in structural analysis include the use of advanced optical
and electron microscopy, including EM tomography, atomic force microscopy,
and dynamic in vivo imaging. Students learn to identify the model
organisms and the appropriate tools and techniques that will allow
them to answer their scientific questions in the most effective
way. Among the model organisms in which training is available are
eukaryotic and prokaryotic viruses, diverse bacteria including cyanobacteria,
Tetrahymena, Saccharomyces and other yeasts, Chlamydomonas, Drosophila,
Caenorhabditis, Arabidopsis and other plant species, mice, and humans.
The program is administered by the Department
of Molecular Genetics and Cell Biology and draws its
internationally distinguished faculty from that department as well
as from a number of others. At a broad level, the research programs
of this faculty seek to reveal the very basic molecular mechanisms
underlying biological phenomena in a cellular context. Major research
foci include the biogenesis of cellular organelles; the assembly
and organization of cellular structures; the coordination, regulation
and four dimensional orchestration of the cell division cycle; the
molecular basis of gene expression and regulation; cellular and
molecular aspects of chromosome recombination and transmission;
molecular and cellular mechanisms of metazoan development; mechanisms
of cell-cell interaction in fertilization, development and disease;
and how cells sense and respond to signals. Students trained in
the program are highly competitive for top postdoctoral positions
and go on to influential careers in basic academic, biomedical,
or industrial research.
Molecular Biosciences (official web site of the PhD Program)
to Graduate Studies in the Molecular Biosciences
• Department of Molecular
Genetics and Cell Biology
• Congratulations to CMB student Sebastian Fica, graduate student in Jonathan P. Staley's lab, on his recent publication in Nature: Fica SM†, Tuttle N†, Novak N, Li N-L, Lu J, Koodathingal P, Dai Q, Staley JP*, and Piccirilli JA*. (2013) RNA catalyzes nuclear pre-mRNA splicing, Nature, 2013 Nov 14;503(7475):229-34. †Co-first authors; *Co-corresponding authors. (PubMed) This was collaborative work with Nicole Tuttle, graduate student in Piccirilli lab. See Nature website for accompanying News & Views, "Metal ghosts in the splicing machine".
• Congratulations to CMB student Angika Basant of Michael Glotzer's lab who is one of two recipients for the TA Award for 2012-2013, for her outstanding work in Molecular Biology of the Cell in Autumn 2012.
• Congratulations to CMB student Jenna Christensen of David Kovar's lab who received a 2013 NSF fellowship.
• Congratulations to CMB student Michael Werner of Alex Ruthenburg's lab who received a 2013 Chicago Biomedical Consortium (CBC) Scholars Award.
• Congratulations to CMB student Adrian Grzybowski of Alex Ruthenburg's lab who is this year's recipient of "Dean's International Student Fellowship".
• Check out Doug Bishop's new paper in Science resolving a long-standing question about meiotic recombination: Rad51 is an accessory factor for Dmc1-mediated joint molecule formation during meiosis. Science. 2012 Sep 7;337(6099):1222-5.
• The Center for Teaching Learning Presents The Workshop on Teaching in the College 2012, September 25-26, 2012. Register Online by September 14, 2012.
• Janet Rowley to receive Japan Prize for role in development of targeted cancer therapy, January 25, 2012, UChicago News
• Repair, mutation, and other topics. Autobiographical sketch by Bernard S. Strauss, PhD, Professor Emeritus, Department of Molecular Genetics and Cell Biology, University of Chicago.
• News Archives